Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238850 | 0.84 | MAPT (0.66) | KMT2ACA1CA2MAPTMEN1 | |
| SCHEMBL3753608 | 0.82 | KDM4E (0.59) | KMT2ACA1CA2MAPTMEN1 | |
| SCHEMBL1528959 | 0.82 | PRKAB2 (0.52) | KMT2ACA1CA2MAPTMEN1 | |
| SCHEMBL2772078 | 0.81 | KMT2A (0.54) | KMT2ACA1CA2MAPTLMNA | |
| SCHEMBL1528932 | 0.79 | KDM4E (0.59) | KMT2ACA1CA2MAPTMEN1 | |
| SCHEMBL2253933 | 0.78 | MAPT (0.62) | KMT2ACA1CA2MAPTMEN1 | |
| SCHEMBL12836646 | 0.78 | CA1 (0.61) | KMT2ACA1CA2MAPTMEN1 | |
| SCHEMBL6535961 | 0.77 | MAPT (0.57) | KMT2ACA1CA2MAPTMEN1 | |
| SCHEMBL15921171 | 0.77 | KMT2A (0.57) | KMT2AMAPTMEN1LMNANPC1 | |
| SCHEMBL12325069 | 0.76 | HSP90AA1 (0.56) | KMT2ACA1CA2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143193-B | Biaryl or heterocyclic biaryl substituted cyclohexene derivative compounds as CETP inhibitors | 株式会社钟根堂 | 2017-12-15 | — | — | CN | disclosed |
| CN-105143193-A | Biaryl or heterocyclic biaryl substituted cyclohexene derivative compounds as CETP inhibitors | CHONG KUN DANG PHARM CORP | 2015-12-09 | — | — | CN | disclosed |