Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 3/20 | 0.32 |
| ▸ | ITPR2 | Q14571 | 1/20 | 0.31 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232799 | 0.98 | ITPR3 (0.31) | ITPR3ITPR2ITPR1 | |
| SCHEMBL2552260 | 0.98 | ITPR3 (0.31) | ITPR3ITPR2ITPR1 | |
| SCHEMBL27475612 | 0.93 | ITPR3 (0.35) | ITPR3ITPR2ITPR1FDPSBLM | |
| SCHEMBL6710152 | 0.89 | ITPR3 (0.33) | ITPR3ITPR2ITPR1FDPSBLM | |
| SCHEMBL29022797 | 0.88 | ITPR3 (0.34) | ITPR3ITPR2ITPR1 | |
| SCHEMBL134178 | 0.86 | ITPR3 (0.37) | ITPR3ITPR2ITPR1FDPSBLM | |
| SCHEMBL544344 | 0.86 | ITPR3 (0.37) | ITPR3ITPR2ITPR1FDPSBLM | |
| SCHEMBL136588 | 0.86 | ITPR3 (0.37) | ITPR3ITPR2ITPR1FDPSBLM | |
| SCHEMBL406797 | 0.86 | ITPR3 (0.37) | ITPR3ITPR2ITPR1FDPSBLM | |
| SCHEMBL12475062 | 0.86 | ITPR3 (0.37) | ITPR3ITPR2ITPR1FDPSBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105026375-A | SHIP1 modulators and methods related thereto | AQUINOX PHARMACEUTICALS INC | 2015-11-04 | — | — | CN | disclosed |