Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19759343 | 0.77 | NR1H2 (0.41) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL21135638 | 0.77 | NR1H2 (0.41) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL16052667 | 0.76 | USP30 (0.40) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL16052666 | 0.76 | USP30 (0.40) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL25048181 | 0.76 | KDM4E (0.39) | KDM4EMAPTTHRBNR1H2GPR119 | |
| SCHEMBL30848770 | 0.75 | USP2 (0.44) | USP2SMN1; SMN2RECQLKDM4EMAPT | |
| SCHEMBL28945961 | 0.75 | PDK4 (0.45) | USP2SMN1; SMN2RECQLKDM4EMAPT | |
| SCHEMBL26136585 | 0.74 | NR1H2 (0.44) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL25047623 | 0.74 | PDK4 (0.39) | USP2SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL25048179 | 0.72 | KDM4E (0.33) | KDM4EMAPTTHRBNR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968654-A | Substituted 2-aminopyridine protein kinase inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2015-10-07 | — | — | CN | disclosed |