Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | DDO | Q99489 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 7/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19326978 | 0.83 | DAO (0.43) | DAODDOCA12CA1CA3 | |
| SCHEMBL15108883 | 0.79 | DAO (0.60) | DAODDOCA12CA1CA3 | |
| SCHEMBL7425258 | 0.77 | PDE3B (0.43) | DAODDOCA12CA1CA3 | |
| SCHEMBL3787127 | 0.74 | KIF11 (0.51) | CA12CA1CA3CA4CA6 | |
| SCHEMBL30946245 | 0.74 | KIF11 (0.51) | CA12CA1CA3CA4CA6 | |
| SCHEMBL16338725 | 0.73 | PDE3B (0.55) | DAODDOCA12CA1CA3 | |
| SCHEMBL31557870 | 0.73 | PDE3B (0.55) | DAODDOCA12CA1CA3 | |
| SCHEMBL429173 | 0.73 | NPC1 (0.45) | DAODDOCA12CA1CA3 | |
| SCHEMBL1082903 | 0.71 | DAO (0.53) | DAODDOCA12CA1CA3 | |
| SCHEMBL3874061 | 0.71 | KDM4E (0.60) | DAODDOCA12CA1CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102453-A | Benzimidazolone derivatives as bromodomain inhibitors | GILEAD SCIENCES INC | 2015-11-25 | — | — | CN | disclosed |