SCHEMBL28036387

SCHEMBL28036387

CCCC(CCC)(c1ccccc1)c1ccc(O)cc1

nearest known ligand 0.84

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 17/20 0.84
ESR2 Q92731 10/20 0.84
ALDH1A1 P00352 1/20 0.55
CYP3A4 P08684 1/20 0.55
AR P10275 1/20 0.53
KIF11 P52732 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272801 0.92 ESR1 (1.00) ESR1ESR2CYP3A4AR
SCHEMBL28036464 0.89 ESR1 (0.85) ESR1ESR2ALDH1A1CYP3A4AR
SCHEMBL5962549 0.87 ESR1 (0.60) ESR1ESR2ARKIF11
Hydrochloric Acid SCHEMBL7846326 0.85 ESR1 (0.58) ESR1ESR2CYP3A4AR
Hydrochloric Acid SCHEMBL7839134 0.85 ESR1 (0.58) ESR1ESR2CYP3A4AR
SCHEMBL6561244 0.84 ESR1 (0.92) ESR1ESR2AR
SCHEMBL312177 0.84 ESR1 (0.59) ESR1ESR2ALDH1A1CYP3A4KIF11
SCHEMBL28757107 0.84 ESR1 (0.59) ESR1ESR2ALDH1A1CYP3A4KIF11
SCHEMBL1334149 0.83 ESR1 (0.83) ESR1ESR2CYP3A4AR
SCHEMBL28613436 0.83 ESR1 (0.83) ESR1ESR2ALDH1A1CYP3A4AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105102422-A Method for producing isocyanate ASAHI KASEI CHEMICALS CORP 2015-11-25 CN disclosed