SCHEMBL272801

SCHEMBL272801

CCCC(CCC)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 17/20 1.00
ESR2 Q92731 9/20 1.00
AR P10275 2/20 0.61
LMNA P02545 1/20 0.48
TYR P14679 1/20 0.48
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
HTR6 P50406 1/20 0.48
ESRRG P62508 1/20 0.48
SLC6A3 Q01959 1/20 0.48
HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28036387 0.92 ESR1 (0.84) ESR1ESR2ARCYP3A4
SCHEMBL6561244 0.92 ESR1 (0.92) ESR1ESR2AR
SCHEMBL1334149 0.91 ESR1 (0.83) ESR1ESR2ARLMNATYR
SCHEMBL11185741 0.90 ESR1 (0.81) ESR1ESR2ARLMNACYP3A4
SCHEMBL4455629 0.88 ESR1 (0.78) ESR1ESR2AR
SCHEMBL28255062 0.88 ESR1 (0.79) ESR1ESR2ARLMNACYP3A4
SCHEMBL9396698 0.88 ESR1 (0.79) ESR1ESR2ARLMNACYP3A4
SCHEMBL11182155 0.88 ESR1 (0.79) ESR1ESR2ARLMNACYP3A4
SCHEMBL11188891 0.88 ESR1 (0.79) ESR1ESR2ARLMNACYP3A4
SCHEMBL9573742 0.86 ESR1 (1.00) ESR1ESR2ARLMNATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3097 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1757634-B2 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER USING SAME IDEMITSU KOSAN CO (JP) 2022-05-25 EP claimed
EP-3235850-B1 POLYCARBONATE COPOLYMER AND PREPARATION METHOD THEREFOR SAMYANG CORP (KR) 2020-02-12 EP claimed
US-10081708-B2 Polycarbonate copolymer and preparation method therefor SAMYANG CORPORATION (KR) 2018-09-25 US claimed
US-20180162994-A1 Polycarbonate Copolymer And Preparation Method Therefor SAMYANG CORPORATION (KR) 2018-06-14 US claimed
EP-3235850-A1 POLYCARBONATE COPOLYMER AND PREPARATION METHOD THEREFOR Samyang Corporation (KR) 2017-10-25 EP claimed
EP-1660560-B1 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-23 EP claimed
CN-103497334-A Copolyetherimides SABIC INNOVATIVE PLASTICS IP 2014-01-08 CN claimed
EP-1581594-B1 POLYCARBONATE MOLDING COMPOSITIONS AND ARTICLES WITH IMPROVED SURFACE AESTHETICS SABIC INNOVATIVE PLASTICS IP (NL) 2013-03-27 EP claimed
US-8222347-B2 Polyester-polycarbonate compositions SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-17 US claimed
JP-4768635-B2 2011-09-07 JP claimed
US-5250655-A Ester interchange catalyst; non-phosgene method MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) 1993-10-05 US claimed
US-5210173-A After dosing at least one-fifth of carbonate precursor, the remaining organic solvent is added in amount at least sufficient to maintain formed polycarbonate in solution GENERAL ELECTRIC COMPANY (US) 1993-05-11 US claimed
EP-0534189-A1 Method for producing polycarbonate MITSUBISHI CHEMICAL CORPORATION (JP) 1993-03-31 EP claimed
EP-0524380-A1 Method of preparing aromatic polycarbonates GENERAL ELECTRIC COMPANY (US) 1993-01-27 EP claimed
US-5041523-A Interfacial polycondensation using divalent phenol and branching agent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1991-08-20 US claimed
US-4816527-A IMPACT STRENGTH MOLDING MATERIALS GENERAL ELECTRIC COMPANY (US) 1989-03-28 US claimed
EP-0303843-A2 Polycarbonate-siloxane polyetherimide copolymer blends GENERAL ELECTRIC COMPANY (US) 1989-02-22 EP claimed
EP-0131643-B1 POLYETHERIMIDE-POLYCARBONATE BLENDS GENERAL ELECTRIC COMPANY (US) 1988-02-17 EP claimed
EP-0217167-A1 A shaped article formed from a blend of a poly(aryl ether) and a polycarbonate and/or a polyarylate AMOCO CORPORATION (US) 1987-04-08 EP claimed
US-4548997-A IMPROVED FLEXURAL AND TENSILE STRENGTH, HIGH HEAT DISTORTION, FLAME RESISTANCE GENERAL ELECTRIC COMPANY (US) 1985-10-22 US claimed