Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | C1R | P00736 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18355266 | 0.82 | KDM4E (0.47) | KDM4EMAPTPOLBCACNA2D1MEN1 | |
| SCHEMBL14322663 | 0.79 | KDM4E (0.44) | KDM4EMAPTPOLBCACNA2D1CLK1 | |
| SCHEMBL16132453 | 0.78 | MAPT (0.47) | KDM4EMAPTDYRK1ACYP3A4MEN1 | |
| SCHEMBL16110993 | 0.78 | MAPT (0.47) | KDM4EMAPTSLC40A1DYRK1ACYP3A4 | |
| SCHEMBL13419576 | 0.77 | SLC40A1 (0.43) | KDM4EMAPTSLC40A1DYRK1AMEN1 | |
| SCHEMBL96953 | 0.77 | SYK (0.57) | KDM4EMAPTKMT2ALMNA | |
| SCHEMBL28178369 | 0.77 | MAPT (0.54) | KDM4EMAPTPOLBCACNA2D1CYP3A4 | |
| SCHEMBL29096082 | 0.77 | SYK (0.57) | KDM4EMAPTKMT2ALMNA | |
| SCHEMBL28146672 | 0.76 | KDM4E (0.48) | KDM4EMAPTPOLBCACNA2D1MEN1 | |
| SCHEMBL16132303 | 0.76 | MAPT (0.44) | KDM4EMAPTSLC40A1DYRK1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102453-A | Benzimidazolone derivatives as bromodomain inhibitors | GILEAD SCIENCES INC | 2015-11-25 | — | — | CN | disclosed |