Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184968 | 1.00 | TLR8 (0.65) | TLR8TP53POLBLMNARECQL | |
| SCHEMBL28036974 | 1.00 | TLR8 (0.65) | TLR8TP53POLBLMNARECQL | |
| SCHEMBL31066866 | 0.88 | TLR8 (0.68) | TLR8TP53POLBLMNARECQL | |
| SCHEMBL31066873 | 0.88 | TLR8 (0.68) | TLR8TP53POLBLMNARECQL | |
| SCHEMBL3059715 | 0.88 | MEN1 (0.64) | TP53POLBLMNARECQLMEN1 | |
| SCHEMBL29968482 | 0.87 | LMNA (0.67) | TLR8TP53POLBLMNARECQL | |
| SCHEMBL29968953 | 0.87 | LMNA (0.67) | TLR8TP53POLBLMNARECQL | |
| SCHEMBL28878994 | 0.87 | LMNA (0.67) | TLR8TP53POLBLMNARECQL | |
| SCHEMBL28879019 | 0.87 | LMNA (0.67) | TLR8TP53POLBLMNARECQL | |
| SCHEMBL28860662 | 0.87 | LMNA (0.67) | TLR8TP53POLBLMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104974138-A | Quinolone benzimidazole compound as well as preparation method and application thereof | UNIV SOUTHWEST | 2015-10-14 | — | — | CN | disclosed |