Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605908 | 0.80 | PIN1 (0.53) | PIN1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27908102 | 0.80 | PIN1 (0.53) | PIN1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27546108 | 0.80 | PIN1 (0.53) | PIN1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11454276 | 0.79 | PIN1 (0.49) | PIN1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5964012 | 0.79 | PIN1 (0.49) | PIN1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22164590 | 0.79 | CYP1A2 (0.42) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL27752471 | 0.78 | PIN1 (0.51) | PIN1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1455978 | 0.78 | PIN1 (0.51) | PIN1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27731921 | 0.78 | PIN1 (0.51) | PIN1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10577078 | 0.77 | PIN1 (0.47) | PIN1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008347-A | Isoquinoline compounds as potassium ion channel inhibitors | BRISTOL MYERS SQUIBB CO | 2015-10-28 | — | — | CN | disclosed |