Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4180717 | 0.88 | GAA (0.45) | GAACYP1A2CA12CA1CA2 | |
| SCHEMBL547427 | 0.81 | CYP1A2 (0.50) | GAACYP1A2CA12CA1CA2 | |
| SCHEMBL1715829 | 0.78 | CYP1A2 (0.53) | GAACYP1A2CA12CA1CA2 | |
| SCHEMBL1715165 | 0.76 | CYP1A2 (0.57) | GAACYP1A2CA12CA1CA2 | |
| SCHEMBL548039 | 0.76 | CYP1A2 (0.50) | GAACYP1A2CA12CA1CA2 | |
| SCHEMBL12527462 | 0.76 | CYP1A2 (0.47) | GAACYP1A2CA12CA1CA2 | |
| SCHEMBL12493846 | 0.76 | CYP1A2 (0.47) | GAACYP1A2CA12CA1CA2 | |
| SCHEMBL14930772 | 0.75 | CYP1A2 (0.55) | GAACYP1A2CA12CA1CA2 | |
| SCHEMBL5089500 | 0.75 | CYP1A2 (0.55) | GAACYP1A2CA12CA1CA2 | |
| SCHEMBL547624 | 0.75 | CYP1A2 (0.46) | GAACYP1A2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003114-A | Diarylhydantoin compounds | 加利福尼亚大学董事会 | 2019-07-12 | — | — | CN | disclosed |
| CN-105037273-B | Diarylhydantoin compounds | 加利福尼亚大学董事会 | 2019-04-19 | — | — | CN | disclosed |
| CN-105037273-A | Diaryl hydantoin compound | UNIV CALIFORNIA | 2015-11-11 | — | — | CN | disclosed |