Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28232909 | 0.89 | EPHX1 (0.33) | EPHX1CA2CA1 | |
| SCHEMBL5286793 | 0.81 | EPHX1 (0.40) | EPHX1CA2CA1MAPK1 | |
| SCHEMBL27525293 | 0.78 | EPHX1 (0.34) | EPHX1CA2CA1MAPK1 | |
| SCHEMBL2326465 | 0.75 | CA2 (0.40) | EPHX1CA2CA1MAPK1 | |
| SCHEMBL8911416 | 0.75 | CA2 (0.40) | EPHX1CA2CA1MAPK1 | |
| SCHEMBL14778630 | 0.75 | EPHX1 (0.33) | EPHX1CA2CA1 | |
| SCHEMBL17651980 | 0.75 | EPHX1 (0.33) | EPHX1CA2CA1 | |
| SCHEMBL5275588 | 0.74 | EPHX1 (0.46) | EPHX1 | |
| SCHEMBL10359016 | 0.74 | TP53 (0.40) | EPHX1 | |
| SCHEMBL3641633 | 0.73 | EPHX1 (0.41) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061436-B | A kind of preparation method of polysubstituted condensed indole diindyl class compound | 清华大学 | 2017-08-11 | — | — | CN | disclosed |
| CN-105061436-A | Preparation method of polysubstituted thick indole and indole compound | UNIV TSINGHUA | 2015-11-18 | — | — | CN | disclosed |