Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10645702 | 0.77 | TSHR (0.62) | KMT2AALDH1A1LMNAMAPTPOLB | |
| SCHEMBL4315131 | 0.76 | TSHR (0.47) | TPMTKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL13812367 | 0.72 | TPMT (0.43) | TPMTALDH1A1HCAR1NPC1TAS1R3 | |
| SCHEMBL28037645 | 0.71 | PARP1 (0.46) | KMT2AALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL5801698 | 0.71 | GSK3B (0.61) | TPMTHCAR1RXRARXRBGSK3B | |
| SCHEMBL19642670 | 0.71 | ALDH1A1 (0.62) | KMT2AALDH1A1LMNAMAPTPOLB | |
| SCHEMBL11974562 | 0.71 | TPMT (0.56) | TPMTKMT2ALMNAMAPTHCAR1 | |
| SCHEMBL30089552 | 0.71 | TPMT (0.56) | TPMTKMT2AALDH1A1HCAR1RXRA | |
| SCHEMBL7457008 | 0.70 | TPMT (0.42) | TPMTKMT2AALDH1A1MAPTHCAR1 | |
| SCHEMBL7977511 | 0.70 | TPMT (0.42) | TPMTKMT2AALDH1A1MAPTHCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164113-A | Pyrroloamide inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | disclosed |