Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | CACNA1I | Q9P0X4 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | ACACB | O00763 | 4/20 | 0.45 |
| ▸ | ACACA | Q13085 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4419844 | 0.92 | DRD2 (0.48) | DRD2CKS1BSKP1SKP2CACNA1I | |
| SCHEMBL13965728 | 0.87 | CACNA1I (0.56) | DRD2CKS1BSKP1SKP2CACNA1I | |
| SCHEMBL7804764 | 0.87 | DRD2 (0.49) | DRD2CKS1BSKP1SKP2CACNA1I | |
| SCHEMBL4419840 | 0.86 | DRD2 (0.48) | DRD2CKS1BSKP1SKP2CACNA1I | |
| SCHEMBL22544222 | 0.86 | CACNA1I (0.52) | DRD2CKS1BSKP1SKP2CACNA1I | |
| SCHEMBL12677719 | 0.85 | DRD2 (0.52) | DRD2CKS1BSKP1SKP2CACNA1I | |
| SCHEMBL12590248 | 0.85 | DRD2 (0.54) | DRD2CKS1BSKP1SKP2ACACB | |
| SCHEMBL24456715 | 0.84 | DRD2 (0.63) | DRD2CKS1BSKP1SKP2ACACB | |
| SCHEMBL27759317 | 0.84 | CACNA1I (0.47) | DRD2CKS1BSKP1SKP2CACNA1I | |
| SCHEMBL7386651 | 0.84 | DRD2 (0.47) | DRD2CKS1BSKP1SKP2CACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153119-A | Pyridylpyrimidyl amine compounds or pyridylpyridyl amine compounds and application thereof | GUANGZHOU KEQIN NEW MEDICINE DESIGN CO LTD | 2015-12-16 | — | — | CN | disclosed |