SCHEMBL28037474

SCHEMBL28037474

O=C1CCCC2N=C3CCCC(=O)C3C=C12

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28037475 0.59
SCHEMBL15656974 0.53 MAPT (0.47) MAPT
SCHEMBL10975426 0.53
SCHEMBL900953 0.52 MAPT (0.70) MAPT
SCHEMBL11181983 0.52 MAPT (0.65) MAPT
SCHEMBL27174144 0.51 MAPT (0.44) MAPT
SCHEMBL289021 0.50
SCHEMBL10719777 0.50 MT-CO2 (0.46) MAPT
SCHEMBL6535460 0.50 MT-CO2 (0.46) MAPT
SCHEMBL4374227 0.50 MT-CO2 (0.46) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105367535-B A kind of method that green catalysis synthesizes 1,8 dioxo decahydro acridine derivatives 马鞍山市泰博化工科技有限公司 2017-07-11 CN claimed
CN-105859619-B The method of the ionic liquid-catalyzed multi-component reaction synthesis acridine cyclohexadione compounds of betaines 河南师范大学 2019-01-01 CN disclosed
CN-105367535-B A kind of method that green catalysis synthesizes 1,8 dioxo decahydro acridine derivatives 马鞍山市泰博化工科技有限公司 2017-07-11 CN disclosed
CN-105859619-A Method for synthesizing acridine diketone compound by catalytic multi-component reaction of betaine ionic liquid 河南师范大学 2016-08-17 CN disclosed
CN-105367535-A Green catalytic synthesis method of 1,8-dioxo-decahydroacridine derivative UNIV ANHUI TECHNOLOGY 2016-03-02 CN disclosed
CN-105367535-A Green catalytic synthesis method of 1,8-dioxo-decahydroacridine derivative UNIV ANHUI TECHNOLOGY 2016-03-02 CN disclosed
CN-105367535-A Green catalytic synthesis method of 1,8-dioxo-decahydroacridine derivative UNIV ANHUI TECHNOLOGY 2016-03-02 CN disclosed