Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ATM | Q13315 | 7/20 | 0.53 |
| ▸ | GLA | P06280 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | CASP1 | P29466 | 5/20 | 0.47 |
| ▸ | CASP7 | P55210 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28473974 | 0.71 | ALDH1A1 (0.58) | ALDH1A1KDM4EATMGLAGAA | |
| SCHEMBL29952780 | 0.71 | ALDH1A1 (0.63) | ALDH1A1KDM4EATMGLAGAA | |
| SCHEMBL28037536 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4EATMGLAGAA | |
| SCHEMBL24590330 | 0.70 | ALDH1A1 (0.73) | ALDH1A1KDM4EATMGLAGAA | |
| SCHEMBL24589380 | 0.70 | ALDH1A1 (0.81) | ALDH1A1KDM4EATMGLAGAA | |
| SCHEMBL4390559 | 0.69 | ALDH1A1 (1.00) | ALDH1A1KDM4EATMGLAGAA | |
| SCHEMBL24590082 | 0.69 | ALDH1A1 (0.76) | ALDH1A1KDM4EATMGLAGAA | |
| SCHEMBL24865073 | 0.68 | ALDH1A1 (0.54) | ALDH1A1KDM4EATMGLAGAA | |
| SCHEMBL22501642 | 0.68 | KDM4E (0.69) | ALDH1A1KDM4EATMGLAGAA | |
| SCHEMBL11296750 | 0.68 | ALDH1A1 (0.78) | ALDH1A1KDM4EATMGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017197-A | Semicarbazone compound preparation method and application in biomedicine | UNIV HUAZHONG NORMAL | 2015-11-04 | — | — | CN | disclosed |