Octicizer

Octicizer

SCHEMBL28037591

CCCCC(CC)COP(=O)(Oc1ccccc1)Oc1ccccc1.OP(O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.57
L3MBTL1 Q9Y468 3/20 0.57
ALDH1A1 P00352 5/20 0.48
CA2 P00918 1/20 0.48
LMNA P02545 3/20 0.44
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
MAPK1 P28482 2/20 0.42
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
KDM4E B2RXH2 1/20 0.39
TSHR P16473 2/20 0.38
HSD17B10 Q99714 1/20 0.38
GLA P06280 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octicizer SCHEMBL93483 0.95 L3MBTL1 (0.64) CYP3A4L3MBTL1ALDH1A1CA2LMNA
Octicizer SCHEMBL18301200 0.95 L3MBTL1 (0.64) CYP3A4L3MBTL1ALDH1A1CA2LMNA
Octicizer SCHEMBL27982284 0.94 CYP3A4 (0.59) CYP3A4L3MBTL1ALDH1A1CA2LMNA
Octicizer SCHEMBL28070819 0.93 L3MBTL1 (0.62) CYP3A4L3MBTL1ALDH1A1CA2LMNA
SCHEMBL124717 0.92 CYP3A4 (0.64) CYP3A4L3MBTL1ALDH1A1CA2LMNA
Octicizer SCHEMBL9798547 0.91 L3MBTL1 (0.59) CYP3A4L3MBTL1ALDH1A1CA2LMNA
SCHEMBL28169101 0.91 CYP3A4 (0.62) CYP3A4L3MBTL1ALDH1A1CA2LMNA
SCHEMBL28112650 0.91 CYP3A4 (0.62) CYP3A4L3MBTL1ALDH1A1CA2LMNA
SCHEMBL28235775 0.91 CYP3A4 (0.62) CYP3A4L3MBTL1ALDH1A1CA2LMNA
SCHEMBL4711504 0.89 CYP3A4 (0.56) CYP3A4L3MBTL1ALDH1A1CA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102112543-B High flow polyvinyl halide compounds and methods of making and using the same POLYONE CORP. (US) 2015-12-09 CN claimed
CN-109477015-A Refrigerator oil and composition for refrigerator 出光兴产株式会社 2019-03-15 CN disclosed
CN-109477014-A Refrigerator oil and composition for refrigerator 出光兴产株式会社 2019-03-15 CN disclosed
CN-105683278-A Method for producing stabilized polymer 株式会社ADEKA 2016-06-15 CN disclosed
CN-105531357-A Refrigerating machine oil composition IDEMITSU KOSAN CO 2016-04-27 CN disclosed
CN-103108944-B Lubricating oil composition for compression type refrigerator IDEMITSU KOSAN CO.,LTD. (JP) 2015-12-16 CN disclosed
CN-102112543-B High flow polyvinyl halide compounds and methods of making and using the same POLYONE CORP. (US) 2015-12-09 CN disclosed