SCHEMBL28037595

SCHEMBL28037595

O=C(O)c1ccc(CCc2ccccn2)c(C(=O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.51
CYP2C19 P33261 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
KDM4E B2RXH2 5/20 0.46
MAPT P10636 1/20 0.46
KDM4C Q9H3R0 2/20 0.44
KDM6B O15054 1/20 0.44
KDM4A O75164 1/20 0.44
KDM5C P41229 1/20 0.44
KDM2A Q9Y2K7 1/20 0.44
KDM3A Q9Y4C1 1/20 0.44
GAA P10253 2/20 0.43
POLB P06746 2/20 0.43
PARP10 Q53GL7 1/20 0.43
ALDH1A1 P00352 1/20 0.43
RAB9A P51151 4/20 0.42
NPC1 O15118 2/20 0.42
LMNA P02545 1/20 0.42
SYK P43405 1/20 0.41
AURKB Q96GD4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4320075 0.84 SMN1; SMN2 (0.50) CYP1A2CYP2C19SMN1; SMN2KDM4EMAPT
SCHEMBL27990964 0.79 KDM4E (0.46) CYP1A2CYP2C19SMN1; SMN2KDM4EMAPT
SCHEMBL8890956 0.79 KDM4E (0.62) KDM4EMAPTKDM4CKDM4AALDH1A1
SCHEMBL27383637 0.79 TSHR (0.51) SMN1; SMN2KDM4EMAPTGAAALDH1A1
SCHEMBL11239545 0.78 CYP1A2 (0.55) CYP1A2CYP2C19SMN1; SMN2KDM4EGAA
SCHEMBL28193524 0.76 TSHR (0.49) SMN1; SMN2KDM4EMAPTGAAPOLB
SCHEMBL28203379 0.75 PTPRA (0.49) CYP1A2CYP2C19SMN1; SMN2KDM4EMAPT
SCHEMBL31691416 0.74 KDM4E (0.45) CYP1A2CYP2C19SMN1; SMN2KDM4EMAPT
SCHEMBL27792967 0.73 KDM4E (0.46) KDM4EMAPTGAAPOLBALDH1A1
SCHEMBL483580 0.73 HRH1 (0.49) CYP1A2CYP2C19SMN1; SMN2KDM4EPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107709533-A Method for oxidation 卡特克塞尔科技有限公司 2018-02-16 CN claimed
CN-104981522-A Oxidatively curable coating composition CATEXEL LTD 2015-10-14 CN claimed
CN-107709533-A Method for oxidation 卡特克塞尔科技有限公司 2018-02-16 CN disclosed
CN-104981522-A Oxidatively curable coating composition CATEXEL LTD 2015-10-14 CN disclosed