SCHEMBL483580

SCHEMBL483580

NC(=O)c1ccccc1CCc1ccccn1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.49
PARP10 Q53GL7 1/20 0.47
AURKA O14965 1/20 0.46
RPS6KB1 P23443 1/20 0.46
CYP1A2 P05177 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
CYP2C19 P33261 1/20 0.45
ADRA1D P25100 1/20 0.44
KDM4E B2RXH2 2/20 0.43
PARP1 P09874 1/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPK1 P28482 1/20 0.42
LMNA P02545 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PTPRA P18433 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29818128 0.85 PARP10 (0.48) HRH1PARP10AURKARPS6KB1CYP1A2
SCHEMBL166483 0.85 PARP10 (0.48) HRH1PARP10AURKARPS6KB1CYP1A2
SCHEMBL4735612 0.82 ALDH1A1 (0.54) CYP2C19KDM4EPARP1ALDH1A1HPGD
SCHEMBL8868841 0.80 ADRA1D (0.44) HRH1PARP10AURKARPS6KB1CYP1A2
SCHEMBL709050 0.80 TAS1R3 (0.61) AURKARPS6KB1SMN1; SMN2ALDH1A1MAPK1
Benzamide SCHEMBL18171705 0.79 PARP10 (0.52) PARP10AURKARPS6KB1CYP1A2SMN1; SMN2
SCHEMBL27714188 0.79 KDM4E (0.46) HRH1PARP10AURKARPS6KB1CYP1A2
SCHEMBL6093499 0.77 AURKA (0.46) PARP10AURKARPS6KB1SMN1; SMN2ADRA1D
SCHEMBL28310418 0.77 AURKA (0.46) PARP10AURKARPS6KB1SMN1; SMN2ADRA1D
SCHEMBL5792277 0.77 AURKA (0.46) PARP10AURKARPS6KB1SMN1; SMN2ADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025012816-A1 FUNGICIDAL COMBINATIONS, METHODS, AND APPLICATIONS THEREOF UPL MAURITIUS LIMITED (MU) 2025-01-16 WO claimed
CN-116096696-A Compositions, agrochemicals, methods for increasing water and nutrient availability and improving pest control in plants and seeds, and uses of said compositions and said agrochemicals 奥克西泰诺工业和贸易公司 2023-05-09 CN claimed
CN-112292035-A Water-dispersible pesticide composition 日本化药株式会社 2021-01-29 CN claimed
US-20210022341-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-01-28 US claimed
US-10827754-B2 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-11-10 US claimed
US-20190014781-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-01-17 US claimed
US-20170000123-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE TRANSPORT OF ELECTRONS OF THE RESPIRATORY CHAIN IN PHYTOPATHOGENIC FUNGAL ORGANISMS BAYER INTELLECTUAL PROPERTY GMBH 2017-01-05 US claimed
US-20160345579-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-12-01 US claimed
US-20160309708-A1 POLYCARBOXYLIC ACID ESTER ALKYL DERIVED FROM BRANCHED AND STRAIGHT ALCOHOL OF PLANT ORIGIN, AND USE OF AN ALKYL ESTER IN AGROCHEMICAL FORMULATIONS OXITENO S.A. INDÚSTRIA E COMÉRCIO (BR) 2016-10-27 US claimed
US-9445590-B2 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the transport of electrons of the respiratory chain in phytopathogenic fungal organisms BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-09-20 US claimed
EP-1570737-A1 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the methionine biosynthesis Bayer CropScience S.A. (FR) 2005-09-07 EP claimed
WO-2005077179-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE MELANIN BIOSYNTHISIS BAYER CROPSCIENCE SA (FR) 2005-08-25 WO claimed
WO-2005077182-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE METHIONINE BIOSYNTHESIS BAYER CROPSCIENCE SA (FR) 2005-08-25 WO claimed
WO-2005077180-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING MITOSIS AND CELL DIVISION BAYER CROPSCIENCE SA (FR) 2005-08-25 WO claimed
WO-2005077901-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE TRANSPORT OF ELECTRONS OF THE RESPIRATORY CHAIN IN PHYTOPATHOGENIC FUNGAL ORGANISMS BAYER CROPSCIENCE SA (FR) 2005-08-25 WO claimed
WO-2005077183-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS BAYER CROPSCIENCE SA (FR) 2005-08-25 WO claimed
WO-2005077181-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE SPORES GERMINATION OR MYCELIUM GROWTH BY ACTING ON DIFFERENT METABOLIC ROUTES BAYER CROPSCIENCE SA (FR) 2005-08-25 WO claimed
EP-1563733-A1 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting mitosis and cell division Bayer CropScience S.A. (FR) 2005-08-17 EP claimed
EP-1563731-A1 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis Bayer CropScience S.A. (FR) 2005-08-17 EP claimed
EP-1563732-A1 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the melanin biosynthesis Bayer CropScience S.A. (FR) 2005-08-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190014781-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS CYP51A1, ERG28, LSS HRH1 3831/4885PARP10 3204/4885AURKA 2099/4885
US-10827754-B2 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis CYP51A1, ERG28, LSS HRH1 3831/4885PARP10 3204/4885AURKA 2099/4885
US-20170000123-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE TRANSPORT OF ELECTRONS OF THE RESPIRATORY CHAIN IN PHYTOPATHOGENIC FUNGAL ORGANISMS SLC25A21, SLC25A1, ETFB HRH1 1740/4885PARP10 3407/4885AURKA 3038/4885
US-20160345579-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS CYP51A1, ERG28, CYP17A1 HRH1 3826/4885PARP10 3108/4885AURKA 1757/4885
US-20210022341-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS ERG28, CYP51A1, CYP21A2 HRH1 1239/4885PARP10 3884/4885AURKA 3670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.