SCHEMBL28037602

SCHEMBL28037602

Cc1cc(C)cc(-c2cc3ccc4cccc5c(-c6cc(C)cc(C)c6)cc(c2)c3c45)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.43
MAOA P21397 2/20 0.43
ERBB2 P04626 1/20 0.43
FYN P06241 1/20 0.43
ACHE P22303 1/20 0.43
AHR P35869 1/20 0.43
ALDH1A1 P00352 5/20 0.42
HPGD P15428 5/20 0.42
HSD17B10 Q99714 5/20 0.42
TSHR P16473 4/20 0.42
CYP3A4 P08684 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
THRB P10828 1/20 0.38
CYP2A6 P11509 2/20 0.38
BRD9 Q9H8M2 1/20 0.36
BRD7 Q9NPI1 1/20 0.36
CYP1A1 P04798 2/20 0.35
CYP1B1 Q16678 2/20 0.35
RXRA P19793 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27703274 0.95 CYP1A2 (0.47) CYP1A2MAOAERBB2FYNACHE
SCHEMBL28037603 0.83 ALDH1A1 (0.52) CYP1A2MAOAERBB2FYNACHE
SCHEMBL27866677 0.80 CYP1A2 (0.40) CYP1A2MAOAERBB2FYNACHE
SCHEMBL15672999 0.80 ALDH1A1 (0.48) CYP1A2MAOAERBB2FYNACHE
SCHEMBL26328449 0.80 CYP1A2 (0.46) CYP1A2MAOAERBB2FYNACHE
SCHEMBL27968027 0.78 CYP1A2 (0.44) CYP1A2MAOAERBB2FYNACHE
SCHEMBL10972428 0.77 CYP1A2 (0.45) CYP1A2MAOAERBB2FYNACHE
SCHEMBL28172005 0.76 CYP1A2 (0.39) CYP1A2MAOAERBB2FYNACHE
SCHEMBL11654321 0.75 CYP1A2 (0.57) CYP1A2MAOAERBB2FYNACHE
SCHEMBL28211576 0.75 CYP1A2 (0.55) CYP1A2MAOAERBB2FYNACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103204996-B Organic electroluminescence device MERCK PATENT GMBH (DE) 2015-12-09 CN disclosed