SCHEMBL28037844

SCHEMBL28037844

CCC(Oc1cccc2ccccc12)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 17/20 0.67
SLC6A2 P23975 15/20 0.67
SLC6A3 Q01959 2/20 0.47
HTR1B P28222 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8285421 0.82 SLC6A4 (0.69) SLC6A4SLC6A2SLC6A3
SCHEMBL27629274 0.81 SLC6A4 (0.60) SLC6A4SLC6A2SLC6A3
SCHEMBL541162 0.81 SLC6A2 (0.68) SLC6A4SLC6A2SLC6A3HTR1B
SCHEMBL28017684 0.81 SLC6A2 (0.68) SLC6A4SLC6A2SLC6A3HTR1B
SCHEMBL9477676 0.80 MCHR1 (0.51) SLC6A4SLC6A2HTR1B
SCHEMBL2722680 0.80 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3
SCHEMBL9995405 0.80 SLC6A4 (0.67) SLC6A4SLC6A2HTR1B
Bromide SCHEMBL6903611 0.80 SLC6A2 (0.66) SLC6A4SLC6A2SLC6A3HTR1B
Bromide SCHEMBL6726247 0.79 SLC6A4 (0.65) SLC6A4SLC6A2HTR1B
SCHEMBL27614221 0.79 SLC6A4 (0.58) SLC6A4SLC6A2SLC6A3HTR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105061230-A Method for preparing dapoxetine hydrochloride KAMP PHARMACEUTICALS CO LTD 2015-11-18 CN disclosed