SCHEMBL28037962

SCHEMBL28037962

O=P(O)(O)Oc1cc2cc(Cl)ccc2[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.49
F3 P13726 1/20 0.49
DAO P14920 1/20 0.49
F11 P03951 1/20 0.45
SIRT1 Q96EB6 1/20 0.44
PYGL P06737 2/20 0.44
FLT3 P36888 1/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
LOXL2 Q9Y4K0 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
CYP19A1 P11511 1/20 0.41
NHERF1 O14745 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6950242 0.87 DAO (0.49) DAOF11FLT3HRH4
SCHEMBL367083 0.78 FLT3 (0.46) DAOFLT3NPC1RAB9ASMN1; SMN2
SCHEMBL3412727 0.75 F7 (0.58) F7F3DAOF11SIRT1
SCHEMBL28351736 0.75 CSNK2A1 (0.39)
SCHEMBL31519052 0.75 CSNK2A1 (0.39)
SCHEMBL31324010 0.74 CSNK2A1 (0.38)
SCHEMBL9538412 0.71 INPPL1 (0.32)
SCHEMBL5185736 0.71 FLT3 (0.41) FLT3MEN1KMT2ANPC1RXFP1
SCHEMBL6507136 0.70 DAO (0.50) DAOPYGLFLT3SMN1; SMN2HRH4
SCHEMBL18886853 0.70 KMT2A (0.54) F7F3DAOSIRT1PYGL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105074470-B Pretreatment method for sample for detecting HBs antigen and use thereof 希森美康株式会社 2016-10-19 CN disclosed
CN-105074470-A Pretreatment method for sample for detecting HBs antigen and use thereof SYSMEX CORP 2015-11-18 CN disclosed