Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.58 |
| ▸ | F3 | P13726 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 3/20 | 0.45 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418189 | 0.87 | ALOX15 (0.52) | F7F3MEN1RAB9AKMT2A | |
| SCHEMBL28795062 | 0.83 | MEN1 (0.59) | F7F3MEN1NPC1RAB9A | |
| SCHEMBL5155719 | 0.81 | SMAD3 (0.57) | FLT3HRH4 | |
| SCHEMBL18886853 | 0.80 | KMT2A (0.54) | F7F3MEN1NPC1RAB9A | |
| SCHEMBL3418659 | 0.80 | PIN1 (0.58) | MEN1NPC1RAB9AKMT2ADAO | |
| SCHEMBL3381954 | 0.80 | FLT3 (0.48) | MEN1NPC1KMT2AFLT3CYP19A1 | |
| SCHEMBL3414863 | 0.80 | KDM4E (0.58) | DAOFLT3KDM4EALDH1A1LMNA | |
| SCHEMBL10969376 | 0.80 | DAO (0.58) | F7F3MEN1NPC1RAB9A | |
| SCHEMBL3419450 | 0.78 | PDGFRB (0.60) | MEN1NPC1RAB9AKMT2AFLT3 | |
| SCHEMBL1833251 | 0.77 | KDM4E (0.55) | NPC1RAB9ADAOFLT3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2505588-B1 | process for preparing AMINOMETHYL AZAADAMANTANE DERIVATIVES as SELECTIVE MODULATORS OF THE ALPHA7- NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR (NNRS) | ABBVIE INC (US) | 2013-11-13 | — | — | EP | claimed |
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | disclosed |
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |