Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 3/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | F3 | P13726 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21358001 | 0.90 | KDM4E (0.44) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL136620 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL136619 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL28414029 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL107841 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL11066677 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL8040612 | 0.78 | ALDH1A1 (0.36) | KDM4EALDH1A1KMT2AMEN1F7 | |
| SCHEMBL8040609 | 0.78 | ALDH1A1 (0.36) | KDM4EALDH1A1KMT2AMEN1F7 | |
| SCHEMBL1975023 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL143886 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189578-B | Sponge polymer with controlled long chain branched and wide molecular weight distribution | 狮子化学盖斯马有限责任公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-105189578-A | Sponge polymer with controlled long chain branching and broad molecular weight distribution | LION COPOLYMER LLC | 2015-12-23 | — | — | CN | disclosed |