Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28038236 | 0.94 | BACE1 (0.33) | BACE1GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL28037913 | 0.87 | GABRA1 (0.42) | BACE1 | |
| SCHEMBL16245756 | 0.82 | GRIN2D (0.33) | GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL16245691 | 0.82 | GRIN2D (0.33) | GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL28038237 | 0.81 | TP53 (0.39) | BACE1GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL28037908 | 0.81 | GABRA1 (0.42) | BACE1 | |
| SCHEMBL16245723 | 0.77 | GRIN2D (0.41) | GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL28037937 | 0.77 | HTR1D (0.37) | — | |
| SCHEMBL16245721 | 0.73 | GRIN2D (0.43) | GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL16245758 | 0.73 | GRIN2D (0.43) | GRIN2DGRIN2AGRIN2BGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189432-A | Improvements in or relating to organic compounds | GIVAUDAN SA | 2015-12-23 | — | — | CN | claimed |
| CN-105189432-A | Improvements in or relating to organic compounds | GIVAUDAN SA | 2015-12-23 | — | — | CN | disclosed |