Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 8/20 | 0.82 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.82 |
| ▸ | BCL2 | P10415 | 6/20 | 0.82 |
| ▸ | RPA1 | P27694 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28038254 | 0.93 | MDM2 (0.80) | MDM2MCL1BCL2RPA1CA9 | |
| SCHEMBL28037907 | 0.90 | MDM2 (0.70) | MDM2MCL1BCL2RPA1CA9 | |
| SCHEMBL13239857 | 0.80 | RPA1 (0.70) | MDM2MCL1BCL2RPA1CA9 | |
| SCHEMBL28037905 | 0.77 | MDM2 (0.63) | MDM2MCL1BCL2SMN1; SMN2 | |
| SCHEMBL9643919 | 0.77 | MALT1 (0.73) | RPA1SMN1; SMN2 | |
| SCHEMBL14504949 | 0.77 | RPA1 (0.58) | MDM2MCL1BCL2RPA1CA9 | |
| SCHEMBL14728116 | 0.76 | SMPD1 (0.64) | RPA1CA9PTGS2SMN1; SMN2 | |
| SCHEMBL9054421 | 0.76 | CA9 (0.65) | MDM2MCL1BCL2RPA1CA9 | |
| SCHEMBL28038235 | 0.75 | SMPD1 (0.67) | RPA1CA9PTGS2SMN1; SMN2 | |
| SCHEMBL3876516 | 0.75 | RPA1 (0.56) | MDM2MCL1BCL2RPA1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061315-A | 1, 5-diphenylpyrazole-3-carboxylic acid compounds and application thereof | UNIV DALIAN TECH | 2015-11-18 | — | — | CN | disclosed |