Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499675 | 0.80 | CLK4 (0.42) | ERAP1PDGFRAMAPK8CDK5CLK4 | |
| SCHEMBL9868 | 0.69 | AKT1 (0.46) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL4240357 | 0.68 | BACE1 (0.37) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL28531472 | 0.68 | AKT1 (0.45) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL6741233 | 0.68 | AKT1 (0.45) | MAPTALDH1A1NPC1RAB9AKMT2A | |
| Phosphonic Acid SCHEMBL28677218 | 0.67 | AKT1 (0.38) | PDGFRACDK5CLK4KDM4EALDH1A1 | |
| Formic Acid SCHEMBL28179543 | 0.67 | AKT1 (0.38) | PDGFRACDK5CLK4KDM4EALDH1A1 | |
| Acetic Acid SCHEMBL27872989 | 0.67 | GAA (0.41) | PDGFRACDK5CLK4MAPTKDM4E | |
| SCHEMBL11711318 | 0.67 | GAA (0.51) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL12989702 | 0.66 | AKT1 (0.48) | MAPTKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061409-A | 1,2,3-triazole substituted diphenyl pyrone compounds, preparation method and applications | UNIV PLA 2ND MILITARY MEDICAL | 2015-11-18 | — | — | CN | disclosed |