Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244239 | 0.77 | ELANE (0.45) | ALOX5HPGDBCL2L1HSD17B10MEN1 | |
| SCHEMBL30218257 | 0.76 | GYS1 (0.39) | BACE1ALOX5HPGDALDH1A1BCL2L1 | |
| SCHEMBL31231553 | 0.74 | AKT1 (0.41) | HPGDALDH1A1BCL2L1HSD17B10BRD4 | |
| SCHEMBL5612902 | 0.74 | AKT1 (0.41) | HPGDALDH1A1BCL2L1HSD17B10BRD4 | |
| SCHEMBL1535884 | 0.73 | BACE1 (0.54) | BACE1ALOX5HPGDALDH1A1BCL2L1 | |
| SCHEMBL9868 | 0.73 | AKT1 (0.46) | HPGDALDH1A1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL27967409 | 0.73 | PTPN22 (0.43) | ALOX5ALDH1A1HSD17B10MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL21412101 | 0.72 | MAOA (0.37) | HPGDALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL6741233 | 0.72 | AKT1 (0.45) | HPGDALDH1A1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL28531472 | 0.72 | AKT1 (0.45) | HPGDALDH1A1SMARCA2SMARCA4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |