Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 14/20 | 0.54 |
| ▸ | FAP | Q12884 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 14/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28038355 | 1.00 | CYP3A4 (0.54) | CYP3A4FAPCYP2D6 | |
| SCHEMBL28038329 | 0.95 | CYP3A4 (0.53) | CYP3A4FAPCYP2D6 | |
| SCHEMBL28038327 | 0.95 | CYP3A4 (0.53) | CYP3A4FAPCYP2D6 | |
| SCHEMBL28038677 | 0.94 | CYP3A4 (0.51) | CYP3A4FAPCYP2D6 | |
| SCHEMBL28038678 | 0.94 | CYP3A4 (0.51) | CYP3A4FAPCYP2D6 | |
| SCHEMBL18256400 | 0.92 | CYP3A4 (0.56) | CYP3A4FAPCYP2D6 | |
| SCHEMBL18256379 | 0.92 | CYP3A4 (0.56) | CYP3A4FAPCYP2D6 | |
| SCHEMBL24808635 | 0.92 | CYP3A4 (0.59) | CYP3A4FAPCYP2D6 | |
| SCHEMBL14417996 | 0.92 | CYP3A4 (0.59) | CYP3A4FAPCYP2D6 | |
| Tenofovir Alafenamide SCHEMBL3107144 | 0.89 | FAP (0.60) | CYP3A4FAPCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105001262-B | The phosphonaminate of aryl substitution and its application medically | 四川海思科制药有限公司 | 2017-09-01 | — | — | CN | disclosed |
| CN-105001262-A | Aryl-substituted phosphonaminate and application in medical science thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-10-28 | — | — | CN | disclosed |