Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | GPR3 | P46089 | 1/20 | 0.55 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19219068 | 0.86 | MAPT (0.47) | MAPTGAANPSR1SMN1; SMN2GPR3 | |
| SCHEMBL5434073 | 0.86 | MAPT (0.60) | MAPTGAANPSR1SMN1; SMN2GPR3 | |
| SCHEMBL18754495 | 0.84 | GPR3 (0.55) | MAPTGAANPSR1SMN1; SMN2GPR3 | |
| Ammonia Solution, Strong SCHEMBL28019425 | 0.82 | GPR3 (0.53) | MAPTGAANPSR1SMN1; SMN2GPR3 | |
| SCHEMBL13758058 | 0.82 | PDE10A (0.60) | MAPTGAANPSR1SMN1; SMN2PDE10A | |
| SCHEMBL31109173 | 0.81 | HSD17B10 (0.56) | MAPTGAANPSR1SMN1; SMN2GPR3 | |
| SCHEMBL4263725 | 0.81 | MAPT (0.47) | MAPTGAANPSR1SMN1; SMN2LMNA | |
| SCHEMBL28142598 | 0.81 | MAPT (0.55) | MAPTGAANPSR1SMN1; SMN2GPR3 | |
| SCHEMBL31109178 | 0.81 | MAPT (0.59) | MAPTGAANPSR1SMN1; SMN2GPR3 | |
| SCHEMBL20792611 | 0.81 | HTT (0.55) | MAPTGAANPSR1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198806-A | Method for synthesizing quinoline by aromatic amine and diketone | UNIV NANYANG NORMAL | 2015-12-30 | — | — | CN | disclosed |
| CN-105175328-A | Method for synthesizing quinoline derivative by utilizing arylamine, aromatic aldehyde and ketone | UNIV NANYANG NORMAL | 2015-12-23 | — | — | CN | disclosed |