Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752217 | 0.90 | EPHX2 (0.69) | EPHX2KMT2AMEN1PRMT1CA12 | |
| SCHEMBL4802418 | 0.84 | MEN1 (0.66) | EPHX2KMT2AMEN1PRMT1CA12 | |
| SCHEMBL1516167 | 0.82 | EPHX2 (1.00) | EPHX2KMT2AMEN1PRMT1CA12 | |
| SCHEMBL28043487 | 0.81 | EPHX2 (0.76) | EPHX2KMT2AMEN1PRMT1CA12 | |
| SCHEMBL694917 | 0.81 | EPHX2 (0.76) | EPHX2KMT2AMEN1PRMT1CA12 | |
| Hydrochloric Acid SCHEMBL27735879 | 0.81 | EPHX2 (0.96) | EPHX2KMT2AMEN1PRMT1CA12 | |
| SCHEMBL2568875 | 0.81 | ALDH1A1 (0.59) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL10054999 | 0.79 | EPHX2 (0.92) | EPHX2KMT2AMEN1PRMT1CA12 | |
| SCHEMBL5462376 | 0.79 | USP2 (0.53) | EPHX2KMT2AMEN1MAPTHTT | |
| SCHEMBL1570274 | 0.78 | MEN1 (0.40) | EPHX2KMT2AMEN1PRMT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103113386-B | Nitrogen heterocyclic substituted-dihydro artemisinin derivative and application thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2015-12-23 | — | — | CN | claimed |