Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28038468 | 1.00 | GBA1 (0.50) | GBA1SLC18A3CCR3MEN1KMT2A | |
| SCHEMBL28038460 | 1.00 | GBA1 (0.50) | GBA1SLC18A3CCR3MEN1KMT2A | |
| SCHEMBL8414906 | 0.89 | SLC18A3 (0.47) | GBA1SLC18A3CCR3MEN1KMT2A | |
| SCHEMBL8414649 | 0.89 | SLC18A3 (0.47) | GBA1SLC18A3CCR3MEN1KMT2A | |
| SCHEMBL5711148 | 0.89 | SLC18A3 (0.47) | GBA1SLC18A3CCR3MEN1KMT2A | |
| SCHEMBL8414652 | 0.89 | SLC18A3 (0.47) | GBA1SLC18A3CCR3MEN1KMT2A | |
| SCHEMBL8414908 | 0.89 | SLC18A3 (0.47) | GBA1SLC18A3CCR3MEN1KMT2A | |
| SCHEMBL8414688 | 0.88 | GBA1 (0.59) | GBA1SLC18A3CCR3MEN1KMT2A | |
| SCHEMBL6977373 | 0.88 | GBA1 (0.59) | GBA1SLC18A3CCR3MEN1KMT2A | |
| SCHEMBL8416050 | 0.88 | GBA1 (0.59) | GBA1SLC18A3CCR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143212-B | Tripeptide epoxy ketone protease inhibitors | 欧尼斯治疗公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-105143212-A | Tripeptide epoxy ketone protease inhibitors | ONYX THERAPEUTICS INC | 2015-12-09 | — | — | CN | disclosed |