SCHEMBL8414906

SCHEMBL8414906

O[C@H]1CCC[C@@H](Cc2ccccc2)C1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.47
GBA1 P04062 1/20 0.47
ALDH1A1 P00352 1/20 0.44
CCR3 P51677 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
MGLL Q99685 1/20 0.42
OPRM1 P35372 1/20 0.42
OPRD1 P41143 1/20 0.42
OPRK1 P41145 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8414908 1.00 SLC18A3 (0.47) SLC18A3GBA1ALDH1A1CCR3MEN1
SCHEMBL8414649 1.00 SLC18A3 (0.47) SLC18A3GBA1ALDH1A1CCR3MEN1
SCHEMBL5711148 1.00 SLC18A3 (0.47) SLC18A3GBA1ALDH1A1CCR3MEN1
SCHEMBL8414652 1.00 SLC18A3 (0.47) SLC18A3GBA1ALDH1A1CCR3MEN1
Cyclohexanol SCHEMBL8424166 0.95 SLC18A3 (0.48) SLC18A3GBA1ALDH1A1CCR3MEN1
SCHEMBL28038468 0.89 GBA1 (0.50) SLC18A3GBA1CCR3MEN1KMT2A
SCHEMBL28038460 0.89 GBA1 (0.50) SLC18A3GBA1CCR3MEN1KMT2A
SCHEMBL6398199 0.89 GBA1 (0.55) SLC18A3GBA1ALDH1A1CCR3MGLL
SCHEMBL28038459 0.89 GBA1 (0.50) SLC18A3GBA1CCR3MEN1KMT2A
SCHEMBL28915739 0.85 GBA1 (0.52) SLC18A3GBA1ALDH1A1CCR3MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863977-B1 PERFUME BASE COMPOSITION KAO CORP (JP) 1999-10-20 EP disclosed
US-5962403-A STABILITY KAO CORPORATION (JP) 1999-10-05 US disclosed
EP-0863977-A1 PERFUME BASE COMPOSITION Kao Corporation (JP) 1998-09-16 EP disclosed
WO-1997006234-A1 PERFUME BASE COMPOSITION KAO CORPORATION (JP) 1997-02-20 WO disclosed