Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR1D | P28221 | 3/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR5A | P47898 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 4/20 | 0.40 |
| ▸ | JAK1 | P23458 | 4/20 | 0.40 |
| ▸ | TYK2 | P29597 | 4/20 | 0.40 |
| ▸ | JAK3 | P52333 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709120 | 0.98 | HTR1A (0.43) | CHEK1HTR1AHTR2CHTR1DHTR1B | |
| SCHEMBL29027761 | 0.87 | CYP4F2 (0.37) | CHEK1HTR1AHTR2CHTR1DHTR1B | |
| SCHEMBL28080162 | 0.86 | MEN1 (0.45) | TSHRMEN1KMT2ALMNAADRA2A | |
| SCHEMBL27699889 | 0.86 | MEN1 (0.45) | TSHRMEN1KMT2ALMNAADRA2A | |
| SCHEMBL27804389 | 0.86 | MEN1 (0.45) | TSHRMEN1KMT2ALMNAADRA2A | |
| SCHEMBL29290752 | 0.86 | MEN1 (0.45) | TSHRMEN1KMT2ALMNAADRA2A | |
| SCHEMBL27721837 | 0.86 | MEN1 (0.45) | TSHRMEN1KMT2ALMNAADRA2A | |
| SCHEMBL20553924 | 0.86 | MEN1 (0.45) | TSHRMEN1KMT2ALMNAADRA2A | |
| SCHEMBL27886029 | 0.84 | MEN1 (0.44) | TSHRMEN1KMT2ALMNAADRA2A | |
| SCHEMBL17474254 | 0.84 | HTR1A (0.42) | HTR1AHTR2CHTR1DHTR1BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045567-B | Phosphatase recruitment chimera (PHORCs) compound based on protein phosphatase 5, preparation method and medical application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-113045567-A | Phosphatase recruitment chimera (PHORCs) compound based on protein phosphatase 5, preparation method and medical application thereof | 中国药科大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-105175715-B | Copolymer and method for preparing monomer for forming the same | 财团法人工业技术研究院 | 2018-03-13 | — | — | CN | disclosed |
| CN-105175715-A | Copolymer and method for preparing monomer for forming the same | IND TECH RES INST | 2015-12-23 | — | — | CN | disclosed |