SCHEMBL28038575

SCHEMBL28038575

CCCCOC(=O)C(C)=CNS(=O)(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
TSHR P16473 4/20 0.49
GAA P10253 2/20 0.48
MMP13 P45452 2/20 0.45
MMP3 P08254 1/20 0.45
KDM4E B2RXH2 1/20 0.45
KAT6A Q92794 1/20 0.45
TDP1 Q9NUW8 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
POLB P06746 1/20 0.43
HPGD P15428 1/20 0.41
EPHX2 P34913 1/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KMT2A Q03164 2/20 0.40
MAPK1 P28482 2/20 0.40
BCAT1 P54687 1/20 0.40
CYP3A4 P08684 1/20 0.40
GLA P06280 1/20 0.40
ADAMTS4 O75173 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2321064 0.76 ALDH1A1 (0.55) ALDH1A1TSHRGAAKDM4EKAT6A
SCHEMBL28296366 0.75 ALDH1A1 (0.48) ALDH1A1TSHRGAAKDM4EKAT6A
SCHEMBL2532167 0.75 KDM4E (0.53) ALDH1A1TSHRKDM4ETDP1L3MBTL1
SCHEMBL8702266 0.75 KDM4E (0.53) ALDH1A1TSHRKDM4ETDP1L3MBTL1
SCHEMBL27679770 0.74 TSHR (0.52) ALDH1A1TSHRGAAMMP13MMP3
SCHEMBL24695128 0.73 TDP1 (0.48) ALDH1A1TSHRGAAMMP13MMP3
SCHEMBL27557322 0.72 TSHR (0.47) ALDH1A1TSHRKDM4ETDP1L3MBTL1
SCHEMBL17105856 0.72 ALDH1A1 (0.47) ALDH1A1TSHRKDM4EHPGD
SCHEMBL27529410 0.72 ALDH1A1 (0.60) ALDH1A1TSHRGAAMMP13MMP3
SCHEMBL27514291 0.72 ALDH1A1 (0.50) ALDH1A1TSHRKDM4ETDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105384867-B A kind of polymer preparing hydrophobicity artificial lens 广东东阳光药业有限公司 2019-05-24 CN claimed
CN-105384867-A Polymer for preparing hydrophobic artificial lens GUANGDONG HEC PHARMACEUTICAL 2016-03-09 CN claimed
CN-105384867-B A kind of polymer preparing hydrophobicity artificial lens 广东东阳光药业有限公司 2019-05-24 CN disclosed
CN-106380550-B A kind of surface tension adjustment shrinkage type polycarboxylate water-reducer and preparation method thereof 广东红墙新材料股份有限公司 2019-03-15 CN disclosed
CN-108003981-A Lubricant composition for gasoline engine and preparation method thereof 中国石油化工股份有限公司 2018-05-08 CN disclosed
CN-108003980-A Lubricant composition for gasoline engine and preparation method thereof 中国石油化工股份有限公司 2018-05-08 CN disclosed
CN-108003972-A Diesel engine lubricating oil composite and preparation method thereof 中国石油化工股份有限公司 2018-05-08 CN disclosed
CN-105585657-B A kind of pour depressant for lubricating oil and preparation method thereof 中国石油化工股份有限公司 2018-03-20 CN disclosed
CN-106380132-B Surface tension adjusts purposes of the shrinkage type polycarboxylate water-reducer in high performance concrete is prepared 广东红墙新材料股份有限公司 2018-03-06 CN disclosed
CN-106242412-B Surface tension adjusts purposes of the shrinkage type polycarboxylate water-reducer in regenerated aggregate concrete is prepared 广东红墙新材料股份有限公司 2018-03-06 CN disclosed
CN-107540783-A Acrylic ester polymer and its application and pour depressant for lubricating oil and preparation method thereof 中国石油化工股份有限公司 2018-01-05 CN disclosed
CN-105524209-B Acrylate based copolymer and its application and pour depressant for lubricating oil and preparation method thereof 中国石油化工股份有限公司 2017-09-29 CN disclosed
CN-106380550-A Surface tension adjustment reduction type polycarboxylate superplasticizer and preparation method thereof 广东红墙新材料股份有限公司 2017-02-08 CN disclosed
CN-106380132-A Application of surface tension adjustment reduction type polycarboxylate superplasticizer in preparing high-performance concrete 广东红墙新材料股份有限公司 2017-02-08 CN disclosed
CN-106242412-A Surface tension adjusts shrinkage type polycarboxylate water-reducer purposes in preparing regenerated aggregate concrete 广东红墙新材料股份有限公司 2016-12-21 CN disclosed
CN-105524209-A Acrylate copolymer, use of acrylate copolymer, lubricating oil pour-point depressant and preparation method of lubricating oil pour-point depressant CHINA PETROLEUM & CHEM CORP 2016-04-27 CN disclosed
CN-105384867-A Polymer for preparing hydrophobic artificial lens GUANGDONG HEC PHARMACEUTICAL 2016-03-09 CN disclosed