Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | MME | P08473 | 8/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.42 |
| ▸ | ACE | P12821 | 4/20 | 0.42 |
| ▸ | CPA1 | P15085 | 3/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28038651 | 1.00 | CA2 (0.54) | CA2MMESOAT1NPC1RAB9A | |
| SCHEMBL8370940 | 0.85 | CA2 (0.54) | CA2MMESOAT1NPC1RAB9A | |
| SCHEMBL29486918 | 0.85 | CA2 (0.54) | CA2MMESOAT1NPC1RAB9A | |
| SCHEMBL8370938 | 0.85 | CA2 (0.54) | CA2MMESOAT1NPC1RAB9A | |
| SCHEMBL28038654 | 0.84 | CA2 (0.52) | CA2MMESOAT1NPC1RAB9A | |
| SCHEMBL1093901 | 0.84 | CA2 (0.52) | CA2MMESOAT1NPC1RAB9A | |
| SCHEMBL30404207 | 0.84 | CA2 (0.52) | CA2MMESOAT1NPC1RAB9A | |
| SCHEMBL28038310 | 0.84 | CA2 (0.52) | CA2MMESOAT1NPC1RAB9A | |
| SCHEMBL1093903 | 0.84 | CA2 (0.52) | CA2MMESOAT1NPC1RAB9A | |
| SCHEMBL28038655 | 0.84 | CA2 (0.52) | CA2MMESOAT1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384807-A | Compositions Containing, Methods Involving, and Uses of Non-Natural Amino Acids and Polypeptides | AMBRX INC | 2016-03-09 | — | — | CN | disclosed |
| CN-101448512-B | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2015-11-25 | — | — | CN | disclosed |