Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | CCR9 | P51686 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658730 | 0.84 | PIK3CB (0.31) | PIK3CB | |
| SCHEMBL28760271 | 0.81 | — | — | |
| SCHEMBL2226803 | 0.79 | PIK3CB (0.38) | PIK3CBCCR9CDC7CDK2 | |
| SCHEMBL27647386 | 0.76 | RAPGEF4 (0.37) | CDC7CDK2 | |
| SCHEMBL27554375 | 0.73 | — | — | |
| SCHEMBL27637862 | 0.73 | RAPGEF4 (0.37) | CDC7CDK2 | |
| SCHEMBL27729177 | 0.73 | IRAK4 (0.33) | — | |
| SCHEMBL28774139 | 0.70 | KMT2A (0.33) | — | |
| SCHEMBL15548780 | 0.68 | PIK3CB (0.62) | PIK3CBCCR9CDC7CDK2 | |
| SCHEMBL30633547 | 0.68 | PIK3CB (0.62) | PIK3CBCCR9CDC7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105392787-A | Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMANN LA ROCHE | 2016-03-09 | — | — | CN | disclosed |