SCHEMBL28038749

SCHEMBL28038749

Nc1ccc(CC(=O)NCC(O)c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.58
CNR2 P34972 4/20 0.55
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
ASAH1 Q13510 1/20 0.51
CNR1 P21554 3/20 0.50
OPRM1 P35372 2/20 0.50
OPRD1 P41143 2/20 0.50
KDM4E B2RXH2 2/20 0.49
TAAR1 Q96RJ0 1/20 0.49
AOC3 Q16853 3/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
TACR1 P25103 1/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27935185 1.00 BCAT2 (0.58) BCAT2CNR2NPC1RAB9ASMN1; SMN2
SCHEMBL8048083 0.89 BCAT2 (0.62) BCAT2CNR2NPC1RAB9ASMN1; SMN2
SCHEMBL8559634 0.84 ADRB3 (0.54)
SCHEMBL9468387 0.79 NPC1 (0.60) CNR2NPC1RAB9ASMN1; SMN2ASAH1
SCHEMBL9244961 0.78 BCAT2 (0.69) BCAT2NPC1RAB9ASMN1; SMN2ASAH1
SCHEMBL11298537 0.77 ADRB3 (0.54) BCAT2CNR2ASAH1CNR1OPRM1
SCHEMBL11652084 0.77 ADRB3 (0.54) BCAT2CNR2ASAH1CNR1OPRM1
SCHEMBL11655875 0.77 ADRB3 (0.54) BCAT2CNR2ASAH1CNR1OPRM1
SCHEMBL11654512 0.77 CNR1 (0.61) BCAT2CNR2NPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL20527920 0.76 BCAT2 (0.67) BCAT2NPC1RAB9ASMN1; SMN2ASAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103232352-B (R)-4-(2-(2-hydroxyl-2-phenylethylamine base) ethyl) anilino carboxylate SUZHOU UUGENE BIOPHARMA CO., LTD. (CN) 2015-12-23 CN disclosed