Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039168 | 1.00 | DPP4 (0.37) | DPP4DPP8DPP9MMP2ANPEP | |
| SCHEMBL3158026 | 1.00 | DPP4 (0.37) | DPP4DPP8DPP9MMP2ANPEP | |
| SCHEMBL28233828 | 0.86 | DPP4 (0.38) | DPP4DPP8DPP9MMP2ANPEP | |
| SCHEMBL2576147 | 0.83 | MMP2 (0.36) | DPP4DPP8DPP9MMP2ANPEP | |
| SCHEMBL6921106 | 0.83 | MMP2 (0.36) | DPP4DPP8DPP9MMP2ANPEP | |
| SCHEMBL1250785 | 0.83 | MMP2 (0.36) | DPP4DPP8DPP9MMP2ANPEP | |
| SCHEMBL12469622 | 0.78 | — | — | |
| SCHEMBL27905688 | 0.78 | — | — | |
| SCHEMBL23038578 | 0.76 | AVPR2 (0.35) | DPP4DPP8DPP9MMP2ANPEP | |
| SCHEMBL23038315 | 0.76 | AVPR2 (0.35) | DPP4DPP8DPP9MMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981457-B | Heterocyclic compound | 武田药品工业株式会社 | 2017-09-19 | — | — | CN | disclosed |
| CN-104981457-A | Heterocyclic compound | TAKEDA PHARMACEUTICAL | 2015-10-14 | — | — | CN | disclosed |