SCHEMBL28039405

SCHEMBL28039405

[CH2]CNc1ccccc1-c1cccc(F)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 2/20 0.51
CHRM3 P20309 4/20 0.40
TAAR1 Q96RJ0 3/20 0.39
POLB P06746 1/20 0.38
MAOB P27338 1/20 0.37
CDC7 O00311 1/20 0.37
ROCK2 O75116 1/20 0.37
MAP4K4 O95819 1/20 0.37
PIM1 P11309 1/20 0.37
PRKACA P17612 1/20 0.37
CDK2 P24941 1/20 0.37
GSK3B P49841 1/20 0.37
HIPK2 Q9H2X6 1/20 0.37
CLK4 Q9HAZ1 1/20 0.37
IRAK4 Q9NWZ3 1/20 0.37
ESR2 Q92731 1/20 0.37
SLC22A12 Q96S37 1/20 0.37
PDK2 Q15119 1/20 0.36
HTT P42858 1/20 0.36
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3906106 0.83 QPCT (0.52) QPCTCHRM3TAAR1POLBMAOB
SCHEMBL28823485 0.81 QPCT (0.48) QPCTCHRM3MAOBLMNAKDM4E
SCHEMBL28039420 0.80 CHRM1 (0.45) CHRM3TAAR1MAPT
SCHEMBL28039342 0.80 ALDH1A1 (0.47) MAOBHTTLMNAMAPTSMN1; SMN2
SCHEMBL4719640 0.77 QPCT (0.45) QPCTCHRM3TAAR1POLBMAOB
SCHEMBL28039655 0.76 ALDH1A1 (0.49) MAOBCLK4SLC22A12LMNATP53
SCHEMBL9311087 0.73 KDM4E (0.44) QPCTCHRM3TAAR1POLBMAOB
SCHEMBL3909899 0.72 HTT (0.51) CHRM3POLBHTTLMNAMAPT
SCHEMBL19503242 0.72 HTT (0.49) TAAR1MAOBCDC7ROCK2MAP4K4
SCHEMBL31168142 0.72 HTT (0.49) TAAR1MAOBCDC7ROCK2MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105017312-A Preparation method of beta-aminoethyl phosphono derivative UNIV SOOCHOW 2015-11-04 CN disclosed