Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 4/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047413 | 0.86 | DPP4 (0.37) | NAMPTACEDPP9DPP7TSHR | |
| SCHEMBL28265026 | 0.82 | ACE (0.36) | ACEDPP9DPP7TSHR | |
| SCHEMBL28186716 | 0.81 | ACE (0.34) | ACEDPP9DPP7 | |
| SCHEMBL28187445 | 0.81 | NOTUM (0.36) | ACETSHRNPSR1 | |
| SCHEMBL27822279 | 0.80 | CHRNB4 (0.36) | ACETSHR | |
| SCHEMBL28152852 | 0.80 | CHRNB4 (0.36) | ACETSHR | |
| SCHEMBL27528106 | 0.79 | KDM4E (0.42) | NAMPT | |
| SCHEMBL27540268 | 0.79 | HTR2C (0.39) | PARP1NAMPTHTR2CHTR2AHTR6 | |
| SCHEMBL20830203 | 0.77 | HTR2C (0.42) | PARP1NAMPTHTR2CHTR2AHTR6 | |
| SCHEMBL27920541 | 0.75 | ACE (0.41) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085515-B | Hydrazide kind compound as coagulation factor xa inhibitors | 华北制药股份有限公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-105085515-A | Hydrazide compound as blood coagulation factor Xa inhibitor | NANJING MINGDE NEW DRUG RES AND DEV CO LTD | 2015-11-25 | — | — | CN | disclosed |