Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70362 | 0.87 | KIF11 (0.71) | KIF11KDM4EALDH1A1HPGDTHRB | |
| SCHEMBL28039675 | 0.85 | KIF11 (0.58) | KIF11KDM4EALDH1A1HPGDTHRB | |
| SCHEMBL17461849 | 0.83 | KIF11 (0.72) | KIF11KDM4EALDH1A1HPGDTHRB | |
| SCHEMBL23830045 | 0.80 | PARP1 (0.68) | KIF11KDM4EALDH1A1HPGDTHRB | |
| SCHEMBL29620678 | 0.80 | PARP1 (0.68) | KIF11KDM4EALDH1A1HPGDTHRB | |
| SCHEMBL69604 | 0.80 | KDM4E (0.67) | KIF11KDM4EALDH1A1HPGDTHRB | |
| SCHEMBL30844878 | 0.80 | KDM4E (0.67) | KIF11KDM4EALDH1A1HPGDTHRB | |
| Hydrochloric Acid SCHEMBL9746959 | 0.79 | KDM4E (0.65) | KIF11KDM4EALDH1A1HPGDTHRB | |
| SCHEMBL15995415 | 0.77 | KIF11 (0.62) | KIF11KDM4EALDH1A1HPGDTHRB | |
| SCHEMBL20515867 | 0.77 | MEN1 (0.59) | KIF11KDM4EALDH1A1HPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008352-A | Carbazole compounds useful as bromodomain inhibitors | BRISTOL MYERS SQUIBB CO | 2015-10-28 | — | — | CN | disclosed |