SCHEMBL28039686

SCHEMBL28039686

CCCCOC(=O)c1ccccc1NC(N)=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.69
L3MBTL1 Q9Y468 3/20 0.69
TDP1 Q9NUW8 2/20 0.69
SMN1; SMN2 Q16637 4/20 0.68
CYP1A2 P05177 1/20 0.68
CYP2C19 P33261 1/20 0.68
ALDH1A1 P00352 9/20 0.64
HSD17B10 Q99714 5/20 0.64
MAPK1 P28482 3/20 0.62
CYP3A4 P08684 2/20 0.62
TP53 P04637 1/20 0.62
KDM4E B2RXH2 7/20 0.62
LMNA P02545 3/20 0.62
MAPT P10636 2/20 0.62
POLB P06746 1/20 0.57
ADRA1D P25100 1/20 0.54
ADRA1A P35348 1/20 0.54
ADRA1B P35368 1/20 0.54
ELANE P08246 1/20 0.52
PRTN3 P24158 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7627192 0.88 TSHR (0.69) TSHRL3MBTL1TDP1SMN1; SMN2CYP1A2
SCHEMBL2137665 0.88 TSHR (0.73) TSHRL3MBTL1TDP1SMN1; SMN2CYP1A2
SCHEMBL3801523 0.86 TSHR (0.64) TSHRL3MBTL1TDP1SMN1; SMN2CYP1A2
SCHEMBL10438008 0.84 KDM4E (0.68) TSHRL3MBTL1TDP1SMN1; SMN2CYP1A2
SCHEMBL15215293 0.84 TSHR (0.69) TSHRL3MBTL1TDP1SMN1; SMN2CYP1A2
SCHEMBL7626813 0.83 ALDH1A1 (0.63) TSHRL3MBTL1TDP1SMN1; SMN2CYP1A2
SCHEMBL7626936 0.83 ALDH1A1 (0.63) TSHRL3MBTL1TDP1SMN1; SMN2CYP1A2
SCHEMBL7630856 0.83 ALDH1A1 (0.63) TSHRL3MBTL1TDP1SMN1; SMN2CYP1A2
SCHEMBL7635559 0.83 ALDH1A1 (0.63) TSHRL3MBTL1TDP1SMN1; SMN2CYP1A2
SCHEMBL3135286 0.83 SMN1; SMN2 (0.82) TSHRL3MBTL1TDP1SMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105579241-B Thermosensitive recording medium 王子控股株式会社 2018-10-16 CN disclosed
CN-105189132-B Thermosensitive recording medium exhibiting gold metallic tone and/or thermosensitive recording medium exhibiting two different tones 王子控股株式会社 2018-06-26 CN disclosed
CN-105579241-A Thermosensitive recording medium OJI HOLDINGS CORP 2016-05-11 CN disclosed
CN-105189132-A Thermosensitive recording medium exhibiting gold metallic tone and/or thermosensitive recording medium exhibiting two different tones OJI HOLDINGS CORP 2015-12-23 CN disclosed