Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826745 | 0.79 | MAOB (0.42) | MAOAMAOBDAOSCN9ASLC6A4 | |
| SCHEMBL18600822 | 0.79 | SLC6A4 (0.49) | MAOAMAOBDAOSCN9ASLC6A4 | |
| SCHEMBL14125786 | 0.79 | SMN1; SMN2 (0.43) | MAOAMAOBDAOSCN9ASLC6A4 | |
| SCHEMBL21261286 | 0.76 | MAOA (0.53) | MAOAMAOBDAOSLC6A4HSD17B10 | |
| SCHEMBL24883472 | 0.76 | SCN9A (0.48) | MAOAMAOBDAOSCN9ASLC6A4 | |
| SCHEMBL1828030 | 0.76 | MAOA (0.42) | MAOAMAOBDAOSCN9AHSD17B10 | |
| SCHEMBL28202737 | 0.76 | SMN1; SMN2 (0.49) | MAOAMAOBDAOSCN9ASLC6A4 | |
| SCHEMBL1830465 | 0.76 | SCN9A (0.48) | MAOAMAOBDAOSCN9ASLC6A4 | |
| SCHEMBL11973719 | 0.75 | CYP11B1 (0.44) | MAOAMAOBDAOSCN9AHSD17B10 | |
| SCHEMBL24883423 | 0.74 | DAO (0.44) | MAOAMAOBDAOSCN9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008367-A | Pyrrolotriazines as potassium ion channel inhibitors | BRISTOL MYERS SQUIBB CO | 2015-10-28 | — | — | CN | disclosed |