Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16403329 | 0.88 | GHSR (0.47) | GHSRALDH1A1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL17685972 | 0.88 | GHSR (0.47) | GHSRALDH1A1SLC6A3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL17686009 | 0.87 | GHSR (0.47) | GHSRALDH1A1SLC6A3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL17686008 | 0.87 | GHSR (0.47) | GHSRALDH1A1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL16401060 | 0.75 | GHSR (0.48) | GHSRSLC6A2SLC6A4 | |
| SCHEMBL70476 | 0.73 | EPOR (0.48) | — | |
| SCHEMBL5655937 | 0.71 | KMT2A (0.56) | ALDH1A1MAPTLMNATDP1 | |
| SCHEMBL12492396 | 0.71 | KMT2A (0.56) | ALDH1A1MAPTLMNATDP1 | |
| SCHEMBL5655931 | 0.71 | KMT2A (0.56) | ALDH1A1MAPTLMNATDP1 | |
| SCHEMBL17691239 | 0.70 | GHSR (0.41) | GHSRALDH1A1SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408331-A | Triazolopyridines as thrombin inhibitors for the treatment of thromboembolic disorders | Bayer Pharma AG | 2016-03-16 | — | — | CN | disclosed |