SCHEMBL28039866

SCHEMBL28039866

Cc1cccc(N=Cc2cnccn2)c1O[SiH](C)C.[H+]

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTH P32929 1/20 0.33
LMNA P02545 1/20 0.31
SCN8A Q9UQD0 1/20 0.30
NOTUM Q6P988 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16098218 0.99 CTH (0.33) CTHLMNASCN8ANOTUMKDM4E
SCHEMBL28039875 0.85 NR4A1 (0.45) LMNASCN8AKDM4EALDH1A1HPGD
SCHEMBL16095251 0.84 CTH (0.35) CTHLMNASCN8ANOTUMKDM4E
SCHEMBL16095252 0.84 CTH (0.35) CTHLMNASCN8ANOTUMKDM4E
SCHEMBL16097204 0.83 NR4A1 (0.46) LMNAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL16096705 0.82 KDM4E (0.34) CTHLMNASCN8ANOTUMKDM4E
SCHEMBL16096706 0.82 KDM4E (0.34) CTHLMNASCN8ANOTUMKDM4E
SCHEMBL28040290 0.81 KDM4E (0.33) CTHNOTUMKDM4E
SCHEMBL17499207 0.81 KDM4E (0.35) CTHLMNAKDM4EALDH1A1HPGD
SCHEMBL17499104 0.80 CTH (0.33) CTHNOTUMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105209268-A Heterocyclic imine functionalized polymers BRIDGESTONE CORP 2015-12-30 CN disclosed