SCHEMBL28040038

SCHEMBL28040038

O=[N+]([O-])OCc1cccc(-c2ccccc2)c1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AGXT P21549 2/20 0.56
NR4A2 P43354 1/20 0.47
TMEM97 Q5BJF2 4/20 0.45
FFAR1 O14842 3/20 0.45
NAAA Q02083 2/20 0.44
AKR1B1 P15121 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
MMP1 P03956 3/20 0.43
MMP2 P08253 3/20 0.43
MMP12 P39900 2/20 0.43
MRGPRX4 Q96LA9 1/20 0.43
MMP9 P14780 2/20 0.43
MGLL Q99685 1/20 0.41
MMP14 P50281 1/20 0.40
ADAM17 P78536 1/20 0.40
GGPS1 O95749 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28088001 0.84 IDO1 (0.52) AGXTTMEM97FFAR1NAAA
SCHEMBL156310 0.83 TSHR (0.48) AGXTTMEM97
SCHEMBL27916932 0.81 TSHR (0.46) AGXTTMEM97
Ammonia Solution, Strong SCHEMBL11782377 0.81 TSHR (0.46) AGXTTMEM97
SCHEMBL1320631 0.79 ALOX15 (0.48) TMEM97
SCHEMBL31464225 0.79 ALOX15 (0.48) TMEM97
Methyl Alcohol SCHEMBL7290164 0.78 TMEM97 (0.47) TMEM97
SCHEMBL3069413 0.77 TMEM97 (0.46) TMEM97MRGPRX4
SCHEMBL17718102 0.77 IDO1 (0.55) MMP2MMP12MMP9
SCHEMBL14394477 0.77 TMEM97 (0.43) TMEM97MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105218377-A A kind of Hydroxytyrosol NO donor derivative and its preparation method and application UNIV XI AN JIAOTONG 2016-01-06 CN claimed
CN-105218377-A A kind of Hydroxytyrosol NO donor derivative and its preparation method and application UNIV XI AN JIAOTONG 2016-01-06 CN disclosed