SCHEMBL28040133

SCHEMBL28040133

CC(C(=O)OC1=CCCC1)=C(CC=O)C1=CCCC1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.34
HDAC2 Q92769 2/20 0.34
HDAC8 Q9BY41 2/20 0.34
HDAC6 Q9UBN7 2/20 0.34
HDAC3 O15379 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28811493 0.85 HDAC4 (0.37) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL1776246 0.82 HDAC4 (0.35) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL8408268 0.82 HDAC4 (0.35) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL147808 0.80 HDAC4 (0.40) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL22578886 0.79 HDAC4 (0.39) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL27885247 0.76 HDAC4 (0.37) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL15665965 0.76 HDAC4 (0.34) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL1684026 0.74 HDAC4 (0.40) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL27524497 0.74 HDAC4 (0.40) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL5500941 0.74 HDAC3 (0.33) HDAC4HDAC2HDAC8HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105026477-A Composition containing cellulose and dispersant DIC HOLDINGS CORP 2015-11-04 CN disclosed