Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499399 | 0.87 | GRIN1 (0.40) | SIGMAR1KCNH2HRH3TAAR1CHRM2 | |
| SCHEMBL17499402 | 0.87 | GRIN1 (0.40) | SIGMAR1KCNH2HRH3TAAR1CHRM2 | |
| SCHEMBL17499786 | 0.79 | SIGMAR1 (0.43) | SIGMAR1KCNH2HRH3TAAR1AOC3 | |
| SCHEMBL16097755 | 0.77 | KDM4E (0.44) | SIGMAR1KCNH2TAAR1AOC3CHRM2 | |
| SCHEMBL4249476 | 0.77 | KMT2A (0.35) | CA12ALDH1A1 | |
| SCHEMBL17499113 | 0.76 | SIGMAR1 (0.43) | SIGMAR1KCNH2HRH3TAAR1AOC3 | |
| SCHEMBL28039851 | 0.76 | SIGMAR1 (0.46) | SIGMAR1KCNH2HRH3TAAR1AOC3 | |
| SCHEMBL16098719 | 0.74 | TAAR1 (0.41) | SIGMAR1KCNH2HRH3TAAR1AOC3 | |
| SCHEMBL16095532 | 0.74 | MEN1 (0.48) | SIGMAR1KCNH2TAAR1AOC3CHRM2 | |
| SCHEMBL17499463 | 0.74 | KMT2A (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209268-B | Heterocyclic imine functionalized polymers | 株式会社普利司通 | 2018-05-04 | — | — | CN | disclosed |
| CN-105209268-A | Heterocyclic imine functionalized polymers | BRIDGESTONE CORP | 2015-12-30 | — | — | CN | disclosed |