SCHEMBL28040523

SCHEMBL28040523

NC(=O)/C(=C(/O)C(=O)O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.52
CYP2C19 P33261 2/20 0.52
TSHR P16473 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
CYP3A4 P08684 2/20 0.52
MAPT P10636 2/20 0.52
BLM P54132 2/20 0.52
POLB P06746 1/20 0.52
PARP1 P09874 1/20 0.52
RECQL P46063 1/20 0.52
PMP22 Q01453 1/20 0.52
HSD17B10 Q99714 1/20 0.52
ALDH1A1 P00352 2/20 0.50
GAA P10253 1/20 0.47
CES1 P23141 3/20 0.44
CES2 O00748 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
ATM Q13315 1/20 0.43
SRD5A2 P31213 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1415252 0.85 TDP1 (0.62) TDP1CYP2C19TSHRL3MBTL1CYP3A4
SCHEMBL7567511 0.85 TDP1 (0.62) TDP1CYP2C19TSHRL3MBTL1CYP3A4
SCHEMBL10497226 0.85 TDP1 (0.62) TDP1CYP2C19TSHRL3MBTL1CYP3A4
SCHEMBL8398051 0.82 CYP2C19 (0.52) TDP1CYP2C19TSHRL3MBTL1CYP3A4
SCHEMBL8397878 0.82 CYP2C19 (0.52) TDP1CYP2C19TSHRL3MBTL1CYP3A4
SCHEMBL5425618 0.79 TDP1 (0.54) TDP1CYP2C19TSHRL3MBTL1CYP3A4
SCHEMBL20610672 0.77 TSHR (0.52) TDP1CYP2C19TSHRL3MBTL1CYP3A4
SCHEMBL28353839 0.77 TSHR (0.52) TDP1CYP2C19TSHRL3MBTL1CYP3A4
SCHEMBL3833664 0.77 TDP1 (0.52) TDP1CYP2C19TSHRL3MBTL1CYP3A4
SCHEMBL27538101 0.77 PTPN1 (0.44) TDP1CYP2C19TSHRL3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104977808-A Black photosensitive resin composite and black matrix made from the black photosensitive resin composite DONGWOO FINE CHEM CO LTD 2015-10-14 CN disclosed