Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497226 | 0.85 | TDP1 (0.62) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL1415252 | 0.85 | TDP1 (0.62) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL7567511 | 0.85 | TDP1 (0.62) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL8104962 | 0.81 | CES1 (0.48) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL5425618 | 0.79 | TDP1 (0.54) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL20610672 | 0.77 | TSHR (0.52) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL28353839 | 0.77 | TSHR (0.52) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL28040523 | 0.77 | TDP1 (0.52) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL14677020 | 0.76 | TSHR (0.50) | TDP1CYP2C19TSHRCYP3A4MAPT | |
| SCHEMBL6432275 | 0.76 | TSHR (0.50) | TDP1CYP2C19TSHRCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8614188-B2 | Inhibiting collagen-induced platelet aggregation and activation with peptide variants | UNIVERSITY OF MASSACHUSETTS (US) | 2013-12-24 | — | — | US | disclosed |
| US-20130040887-A1 | Inhibiting Collagen-Induced Platelet Aggregation and Activation with Peptide Variants | UNIVERSITY OF MASSACHUSETTS | 2013-02-14 | — | — | US | disclosed |
| US-8278271-B2 | Inhibiting collagen-induced platelet aggregation and activation with peptide variants | UNIVERSITY OF MASSACHUSETTS (US) | 2012-10-02 | — | — | US | disclosed |
| EP-2101802-A2 | INHIBITING COLLAGEN-INDUCED PLATELET AGGREGATION AND ACTIVATION WITH PEPTIDE VARIANTS | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (US) | 2009-09-23 | — | — | EP | disclosed |
| US-20090075899-A1 | Inhibiting collagen-induced platelet aggregation and activation with peptide variants | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 2009-03-19 | — | — | US | disclosed |
| WO-2008076275-A2 | INHIBITING COLLAGEN-INDUCED PLATELET AGGREGATION AND ACTIVATION WITH PEPTIDE VARIANTS | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075899-A1 | Inhibiting collagen-induced platelet aggregation and activation with peptide variants | GP6, SELPLG, F13B | TDP1 3481/4885CYP2C19 1429/4885TSHR 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.